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Rabbit anti-PIK3C3/hVPS34 [+Biotin]

Rabbit anti-PIK3C3/hVPS34 [+Biotin]

Manufacturer	Raybiotech
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Adenocarcinoma Mesothelioma ELISA Autophagy Cardiovascular Research Proliferation Myocardial Infarction Primary Antibodies
Type	Antibody
Specific against	Human
Isotype	IgG
Format	Supplied as 200 ug of purified and lyophilized antibody. The antibody is stable for at least one year from the date of receipt when stored at -20C to -70C. Reconstituted antibody (suggesting with sterile PBS containing 0.1% BSA) can also be aliquotted and
Applications	ELISA
Amount	50 ug
Host	Rabbit
Item no.	RB-08-0037B-50
Targets	PI3K;;PIK3C3
eClass 6.1	32160702
eClass 9.0	32160702
Available
Target Name	PIK3C3/hVPS34
Accession Number	NM_002647.2
Conjugate/Tag/Label	Biotin
Application notes:	ELISA (recommended work dilution= 1:32, 000 (Minimum detecting ability 30 ng/ml))
Product Description	The Class III PI3K (phosphoinositide 3-kinase), Vps34 (vacuolar protein sorting 34), was first identified in yeast, then it was also defined in mammalian cells of different species, including human, designated as hVPS34. Investigations shown that it could play an important role in the ability of cells to respond to changes in nutrient conditions. In both yeast and mammalian cells, Class III PI3Ks are also required for the induction of autophagy during nutrient deprivation. Finally, mammalian hVPS34 is itself regulated by nutrients. Thus Class III PI3Ks are implicated in the regulation of both autophagy and, through the mTOR pathway, protein synthesis, and thus contribute to the integration of cellular responses to changing nutritional status.
Immunogen	Immunogen was synthetic peptide derived from Human hVPS34. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.