Antibodies

Rabbit anti-Hepcidin [+Biotin]

Hersteller Raybiotech
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Format Supplied as lyophilized purified antibody. The antibody can be reconstituted in sterile PBS, be stored at 4C for 1 month after resuspension. Please avoid freeze-thaw cycles.
Applikationen ELISA
Menge 50 ug
Host Rabbit
ArtNr RB-13-0005B-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Target Name
Hepcidin
Accession Number
P81172
Gene Symbol
HAMP
Gene ID
57817
Target Synonyms
LEAP-1, HEPC, HFE2B, LEAP1
Conjugate/Tag/Label
Biotin
Application notes:
ELISA (recommended work dilution= 1:10e6 (at least)), Western Blotting (recommended work dilution= 2-5 ug/mL)
Product Description
Hepcidin, also called as LEAP-1 is cysteine-rich peptide containing four disulfide bonds. Its active form, 25-residue peptide was identified in human blood. It was predominantly detected in the liver, and, to a much lower extent, in the heart. Gram-positive Bacillus megaterium, Bacillus subtilis, Micrococcus luteus, Staphylococcus carnosus, and Gram-negative Neisseria cinerea as well as the yeast Saccharomyces cerevisiae dose-dependently exhibited sensitivity upon treatment with synthetic Hepcidin. It is also the central regulator of systemic iron homeostasis. Dysregulation of hepcidin production results in a variety of iron disorders. Hepcidin deficiency is the cause of iron overload in hereditary hemochromatosis, iron-loading anemias, and hepatitis C. Hepcidin excess is associated with anemia of inflammation, chronic kidney disease and iron-refractory iron deficiency anemia.
Immunogen
Immunogen was synthetic peptide derived from Human Hepcidin. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction will be purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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Menge: 50 ug
Lieferbar: In stock
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