Anti-Mouse beta-Glucan Receptor Antibody

Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation

Blue ice

12 months from the date of shipment when stored properly.

Purified IgG - liquid

beta-Glucan Receptor

IgG concentration 1.0 mg/ml (lot specific)

This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells.As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens.Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.