« Zurück
Home /
Recombinant Human LEPTIN

Recombinant Human LEPTIN

ArtNr	229-20189
Hersteller	Raybiotech
Menge	1 mg
Kategorie	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Obesity Endocrine Regulation of Lipid Metabolism
Typ	Proteins
Format	Lyophilized
Applikationen	WB, ELISA, FA
Specific against	Human (Homo sapiens)
Host	Hamster - Armenian
Purity	>98% by SDS PAGE and HPLC analysis.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Proteins and Peptides\|Recombinant Proteins
Shipping Temperature	Ambient temperature
Storage Conditions	-20°C
Molecular Weight	16.0kD (147 amino acid residues).
Description	Purified recombinant leptin expressed in E.coli. Sterile filtered through a 0.2 micron filter.
Format	Purified recombinant protein - lyophilized
Formulation	Lyophilized with 0.1% TFA
Protein Name & Synonyms	LEPTIN
UNSPSC Code	12352202
Concentration	ca.1.0 mg/ml after reconstitution
Reconstitution	Reconstitute with 1.0 ml distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution. For extended storage, the addition of 0.1% bovine serum abumin (BSA) is recommended.
Endotoxin Level	<1EU/ug
Preservative	None present
Introduction	Leptin is a major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. Secreted leptin associates with proteins within the bloodstream and is transported to the brain, where it inhibits or up-regulates the activity of neuropeptides such as neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone respectively. Leptin is a recognised marker of obesity, with a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones.
Biological activity	129-20189 is biologically active in the ob/ob mouse obesity model. The ob/ob mice were treated via intraperitoneal injection once daily at a dose of 5 µ g Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

229-20189.pdf

229-20189-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 1 mg

lieferbar

Lieferung vsl. bis 31.07.2025

Express-Lieferung: 1 Tage sparen

Vergleichen

Auf den Wunschzettel

Weiterempfehlen per Mail