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Recombinant Human PAI-1

Recombinant Human PAI-1

ArtNr	229-20190
Hersteller	Raybiotech
Menge	10 ug
Kategorie	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Senescence By Organ Breast Cancer Pancreatic Cancer Functional Assays
Typ	Proteins
Format	Lyophilized
Applikationen	FA
Specific against	Human (Homo sapiens)
Host	Hamster - Armenian
Purity	>95% by SDS PAGE and HPLC analysis.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Proteins\|Recombinant Proteins\|Human Proteins
Shipping Temperature	Ambient temperature
Storage Conditions	-20°C
Molecular Weight	42.7kD (379 amino acid residues).
Description	Purified recombinant PAI-1 expressed in E.coli.
UNSPSC Code	12352202
Formulation	10mM Sodium Phosphate
Protein Name & Synonyms	PAI-1,
Format	Purified recombinant protein - lyophilized
Concentration	~0.1mg/ml after reconstitution
Reconstitution	Reconstitute with 100ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution. For extended sotrage, the addition of 0.1% BSA is recommended.
Endotoxin Level	<1EU/ug
Preservative	None present
Biological activity	Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37°, C. Half maximal inhibition against 1.0 ug/ml of single chain tPA was obtained at a concentration of 2.0 ug/ml.
Introduction	PAI-1 (plasminogen activator inhibitor-1) is a serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis. Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

229-20190.pdf

229-20190-datasheet.pdf

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Menge: 10 ug

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Lieferung vsl. bis 13.11.2025

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