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Recombinant Human INTERLEUKIN-22

Recombinant Human INTERLEUKIN-22

Manufacturer	Raybiotech
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	10 ug
Item no.	229-20197
eClass 6.1	34160400
eClass 9.0	42020190
Available
Short Description	Purified recombinant IL-22 expressed in E.coli
Introduction	Interleukin-22 (IL-22) is a regulatory cytokine and member of the IL-10 family, secreted by activated T cells, which signals through a class II cytokine receptor system consisting of IL-22R and IL-10R-beta/CRF2-4. IL-22 has been shown to act as an inhibitor of the production of IL-4 by Th2 cells, up-regulate the production of acute phase reactants in the pancreas and liver, and to be up-regulated in intestinal inflammation associated with Crohn’s disease.
Protein Name	IL-22
Molecular Weight (kDa)	33.6kD (146 amino acid homodimer)
Purity	>98% by SDS PAGE and HPLC analysis
Concentration	ca.0.1mg/ml
Preservative	None present
Endotoxin Level	<1EU/ug
Protein Type	Recombinant Protein
Recommended Applications	Functional Assays
Biological activity	Determined by its ability to activate STAT following receptor ligand interaction.
Reconstitution	Reconstitute with 100ul distilled water Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommends that the vial is gently mixed after reconstitution.
Storage/stability	Prior to reconstitution store at +4° C. After reconstitution store at -20° C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for3 months from date of reconstitution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.