Melatonin (standard)

ArtNr	HY-B0075R-100mg
Hersteller	MedChem Express
CAS-Nr.	73-31-4
Menge	100 mg
Quantity options	1 ea 100 mg 250 mg 25 mg 50 mg
Kategorie	Reagents & Chemicals Standards, Ladders & Markers Other Standards
Typ	Standard
Specific against	other
Citations	[3]Rahim I, et al. Melatonin administration to wild-type mice and non-treated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis. J Pineal Res. 2017 Mar 31\|[4]Bu LJ, et al. Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation. World J Gastroenterol. 2017 Feb 14;23(6):986-998.\|[5]Zhi Chen, et al. Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress. J Ovarian Res. 2019 May 10;12(1):43.\|[1]Kilic U, et al. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice. Redox Biol. 2017 Apr 5;12:657-665\|[2]Hu C, et al. Neuroprotective effect of melatonin on soluble Aβ1-42-induced cortical neurodegeneration via Reelin-Dab1 signaling pathway. Neurol Res. 2017 Apr 7:1-1
Smiles	CC(NCCC1=CNC2=C1C=C(OC)C=C2)=O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	N-Acetyl-5-methoxytryptamine (standard),Melatonin
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Apoptosis; Autophagy; Endogenous Metabolite; Melatonin Receptor; Mitophagy; Reference Standards
Shipping Temperature	Room temperature
Molecular Weight	232.283
Product Description	Melatonin (Standard) is the analytical standard of Melatonin. This product is intended for research and analytical applications. Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Manufacturer - Pathway	Apoptosis; Autophagy; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Clinical information	No Development Reported

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Menge: 100 mg

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