SU 5402

Blue Ice

296, 32

Yellow-Green Solid

A specific FGFR (fibroblast growth factor receptor) inhibitor. Also an intermediate for 3-(hetero)arylmethylidene-2-indolinone derivatives as modulators of protein kinase activity for use in treating cancer.

Synonyms;
2-[(1, 2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic Acid; 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone

CAS Number:
215543-92-3

Molecular Formula:
C₁₇H₁₆N₂O₃

Melting Point:
>148ºC (dec.)

Solubility:
DMSO (Slightly), Methanol (Slightly, Sonicated)

Form:
Pale Yellow to Dark Brown Solid

Storage and Stability:
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.