Prazosin

ArtNr	HY-B0193-100mg
Hersteller	MedChem Express
CAS-Nr.	19216-56-9
Menge	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 5 mg
Kategorie	Reagents & Chemicals Biochemicals
Typ	Chemicals
Specific against	other
Purity	99.80
Citations	[1]Day HE, et al. Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic receptor mRNA in the rat brain and spinal cord. J Chem Neuroanat. 1997 Jul;13(2):115-39.\|[2]Elizabeth K Lucas, et al. Prazosin during fear conditioning facilitates subsequent extinction in male C57Bl/6N mice. Psychopharmacology (Berl). 2019 Jan;236(1):273-279.\|[3]Loukia Katsouri, et al. Prazosin, an α(1)-adrenoceptor antagonist, prevents memory deterioration in the APP23 transgenic mouse model of Alzheimer's disease. Neurobiol Aging. 2013 Apr;34(4):1105-15. \|[4]Umit Kazim Ozdoğan, et al. Influence of prazosin and clonidine on morphine analgesia, tolerance and withdrawal in mice. Eur J Pharmacol. 2003 Jan 24;460(2-3):127-34. Am J Pathol. 2023 Apr 21;S0002-9440(23)00132-3.\|Biomed Pharmacother. 2020 Apr;124:109731.\|Cells. 2023 May 24, 12(11), 1461.\|Drug Des Devel Ther. 2024 Apr 9:18:1103-1114.\|Elife. 2024 May 29.\|J Med Chem. 2021 Mar 11;64(5):2725-2738.\|bioRxiv. 2024 November 03.\|BMC Pulm Med. 2021 Jun 5;21(1):189.\|Cell Discov. 2023 Feb 7;9(1):16.\|Cell Rep Med. 2024 Oct 1:101771.\|iScience. 2025 Jan 17;28(2):111831.\|J Exp Med. 2023 Nov 6;220(11):e20230577.\|J Transl Med. 2022 Oct 2;20(1):444.
Smiles	O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)C4=CC=CO4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Adrenergic Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, stored under nitrogen)
Molecular Weight	383.40
Product Description	Prazosin is an α-adrenergic receptor antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimer’s disease[1][2][3][4].
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO: 41.67 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	Launched

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HY-B0193-100mg-safety-datasheet.pdf