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Human metapneumovirus Post-fusion glycoprotein F0, His Tag (MALS verified) Europäischer Partner

ArtNr RSF-V52H5-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 90%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Versandbedingung Raumtemperatur
Lieferbar
Specificity Human metapneumovirus (strain CAN97-83)
Manufacturer - Category
Protein / Viral Proteins
Manufacturer - Conjugate / Tag
C-10×His, Unconjugated
Manufacturer - Species
Human metapneumovirus (strain CAN97-83)
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
56.6 kDa
Description
Human metapneumovirus Post-fusion glycoprotein F0, His Tag (RSF-V52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 19- Thr 489 (Accession # Q6WB98).
Background
Human metapneumovirus (hMPV) is a paramyxovirHMPV G protein has not been shown to possess either hemagglutination or neuraminidase activity. Recombinant HMPV lacking the G protein replicates at levels similar to wild-type virus in vitro, but exhibits reduced titers in v ivo . One report suggested that HMPV G serves as an attachment protein and binds to cell surface glycosaminoglycans and thus may have a true attachment function us that is a common cause of bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) glycoprotein is the primary target of neutralizing antibodiesand is thus a critical vaccine antigen.
Molecule
Postfusion glycoprotein F0/post-F protein (HMPV)
Exp Region
Leu 19- Thr 489
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 56.6 kDa. The protein migrates as 51-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin
1.0 EU per μg
Buffer
0.1 M Sodium citrate, 0.5 M Arginine, pH5.5
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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