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Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Detergent)

Human SLC7A11&SLC3A2 Full Length Protein, Flag,His Tag (Detergent)

ArtNr	SLS-H52D3-20ug
Hersteller	ACROBiosystems
Menge	20 ug
Quantity options	100 ug 20 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, FLAG
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-Flag & C-10xHis & N-10xHis, Unconjugated
Shipping Temperature	Dry ice
Storage Conditions	-70°C
Molecular Weight	59.4 kDa & 69.9 kDa
Manufacturer - Format	Liquid
Description	Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
Background	Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring specialised transport systems for its import into the cell. System xc- is a dedicated cystine transporter, importing cystine in exchange for intracellular glutamate. To counteract elevated levels of reactive oxygen species in cancerous cells system xc- is frequently upregulated, making it an attractive target for anticancer therapies.
Molecule	SLC7A11 & SLC3A2
Exp Region	Val 2 - Leu 501 & Glu 2 - Ala 630
Characteristics	The SLC7A11 protein carries a Flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The SLC3A2 protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 59.4 kDa & 69.9 kDa.
Endotoxin	1.0 EU per μg
Buffer	50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 3 months under sterile conditions.
Protectant	glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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SLS-H52D3-20ug-datasheet.pdf

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Menge: 20 ug

lieferbar

Lieferung vsl. bis 19.02.2026

Express-Lieferung: 6 Tage sparen

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