Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse, Rat |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ112531-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q96KG7 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_001295048. 1). |
Short Description |
Rabbit polyclonal against MEGF10 |
Cellular localization |
Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionPhagocytic CupEnriched At The Sites Of Contact With Apoptotic Thymocyte CellsForms An IrregularMosaic-Like Adhesion Pattern In Region Of The Cell Surface That Becomes Firmely Fixed To The SubstrateExpressed At The Cell Surface In Clusters Around Cell Corpses During EngulfmentDuring The Engulfment Of Apoptotic ThymocytesRecruited At The Bottom Of The Forming Phagocytic CupColocalizes With Abca1 In Absence Of Any Phagocytic ChallengeDoes Not Localize Within LamellipodiaDoes Not Localize With Megf11 |
Molecular weight |
Calculated: 60kDa/122kDa. Observed: 122kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Multiple Epidermal Growth Factor-Like Domains Protein 10 antibodyAnti-Multiple Egf-Like Domains Protein 10 antibodyAnti-MEGF10 KIAA1780 antibody |
Protein name |
Multiple Epidermal Growth Factor-Like Domains Protein 10Multiple Egf-Like Domains Protein 10 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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