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Anti-MEGF10 antibody

Anti-MEGF10 antibody

Manufacturer	St John's Laboratory
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Applications	WB
Amount	50ul
Host	Rabbit
Item no.	STJ112531-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q96KG7
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.
Gene ID	84466
Gene symbol	MEGF10
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_001295048. 1).
Short Description	Rabbit polyclonal against MEGF10
Cellular localization	Cell Membrane Single-Pass Type I Membrane Protein Cell Projection Phagocytic Cup Enriched At The Sites Of Contact With Apoptotic Thymocyte Cells Forms An Irregular Mosaic-Like Adhesion Pattern In Region Of The Cell Surface That Becomes Firmely Fixed To The Substrate Expressed At The Cell Surface In Clusters Around Cell Corpses During Engulfment During The Engulfment Of Apoptotic Thymocytes Recruited At The Bottom Of The Forming Phagocytic Cup Colocalizes With Abca1 In Absence Of Any Phagocytic Challenge Does Not Localize Within Lamellipodia Does Not Localize With Megf11
Molecular weight	Calculated: 60kDa/122kDa. Observed: 122kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Multiple Epidermal Growth Factor-Like Domains Protein 10 antibody Anti-Multiple Egf-Like Domains Protein 10 antibody Anti-MEGF10 KIAA1780 antibody
Protein name	Multiple Epidermal Growth Factor-Like Domains Protein 10 Multiple Egf-Like Domains Protein 10
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	MEG10_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

available

Delivery expected until 5/23/2024