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Anti-PKM antibody Europäischer Partner

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ115844-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Alias Anti-Pyruvate Kinase Pkm antibody</br>Anti-Cytosolic Thyroid Hormone-Binding Protein antibody</br>Anti-Cthbp antibody</br>Anti-Opa-Interacting Protein 3 antibody</br>Anti-Oip-3 antibody</br>Anti-Pyruvate Kinase 2/3 antibody</br>Anti-Pyruvate Kinase Muscle
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
P14618
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Gene ID
Gene symbol
PKM
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 11-221 of human PKM (NP_002645. 3).
Short Description
Rabbit polyclonal against PKM
Tissue specificity
Specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells.
Cellular localization
Cytoplasm
Nucleus
Translocates To The Nucleus In Response To Different Apoptotic Stimuli
Nuclear Translocation Is Sufficient To Induce Cell Death That Is Caspase Independent
Isoform-Specific And Independent Of Its Enzymatic Activity
Molecular weight
Calculated: 56kDa/57kDa/58kDa. Observed: 65kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Pyruvate Kinase Pkm antibody
Anti-Cytosolic Thyroid Hormone-Binding Protein antibody
Anti-Cthbp antibody
Anti-Opa-Interacting Protein 3 antibody
Anti-Oip-3 antibody
Anti-Pyruvate Kinase 2/3 antibody
Anti-Pyruvate Kinase Muscle Isozyme antibody
Anti-Thyroid Hormone-Binding Protein 1 antibody
Anti-Thbp1 antibody
Anti-Tumor M2-Pk antibody
Anti-P58 antibody
Anti-PKM OIP3 PK2 PK3 PKM2 antibody
Protein name
Pyruvate Kinase Pkm
Cytosolic Thyroid Hormone-Binding Protein
Cthbp
Opa-Interacting Protein 3
Oip-3
Pyruvate Kinase 2/3
Pyruvate Kinase Muscle Isozyme
Thyroid Hormone-Binding Protein 1
Thbp1
Tumor M2-Pk
P58
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ul
Lieferbar: In stock
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