Vergleich

Anti-AKT1 antibody (250-330) Europäischer Partner

ArtNr STJ91548-200
Hersteller St John's Laboratory
Menge 200 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody, Anti-Protein Kinase B antibody, Anti-Pkb antibody, Anti-Protein Kinase B Alpha antibody, Anti-Pkb Alpha antibody, Anti-Proto-Oncogene C-Akt antibody, Anti-Rac-Pk-Alpha antibody, Anti-AKT1 PKB RAC antibody
Similar products Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody
Anti-Protein Kinase B antibody
Anti-Pkb antibody
Anti-Protein Kinase B Alpha antibody
Anti-Pkb Alpha antibody
Anti-Proto-Oncogene C-Akt antibody
Anti-Rac-Pk-Alpha antibody
Lieferbar
Storage Conditions
Store at-20°C, and avoid repeat freeze-thaw cycles.
Molecular Weight
55 kDa
Description
Rabbit polyclonal to Akt1.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1 mg/ml
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
250-330 aa
Tissue specificity
Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Cellular localization
Cytoplasm
Nucleus
Cell Membrane
Nucleus After Activation By Integrin-Linked Protein Kinase 1 (Ilk1)
Nuclear Translocation Is Enhanced By Interaction With Tcl1a
Phosphorylation On Tyr-176 By Tnk2 Results In Its Localization To The Cell Membrane Where It Is Targeted For Further Phosphorylations On Thr-308 And Ser-473 Leading To Its Activation And The Activated Form Translocates To The Nucleus
Colocalizes With Wdfy2 In Intracellular Vesicles
Clonality
Polyclonal
Protein name
Rac-Alpha Serine/Threonine-Protein Kinase
Protein Kinase B
Pkb
Protein Kinase B Alpha
Pkb Alpha
Proto-Oncogene C-Akt
Rac-Pk-Alpha
Gene symbol
AKT1
Dilution range
WB 1:500-1:2000
ELISA 1:20000
Note
For Research Use Only (RUO).
Immunogen Region
250-330 aa
Short Description
Rabbit polyclonal against Akt1

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