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Anti-Akt1 antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB, ELISA
Menge 200ul
Host Rabbit
ArtNr STJ91548-200
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID
P31749
Storage
Store at-20° C, and avoid repeat freeze-thaw cycles.
Concentration
1 mg/ml
Description
Rabbit polyclonal to Akt1.
Gene ID
207
Gene symbol
Immunogen
Synthesized peptide derived from human Akt around the non-phosphorylation site of T308.
Immunogen region
250-330 aa
Short Description
Rabbit polyclonal against Akt1
Tissue specificity
Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Cellular localization
Cytoplasm
Nucleus
Cell Membrane
Nucleus After Activation By Integrin-Linked Protein Kinase 1 (Ilk1)
Nuclear Translocation Is Enhanced By Interaction With Tcl1a
Phosphorylation On Tyr-176 By Tnk2 Results In Its Localization To The Cell Membrane Where It Is Targeted For Further Phosphorylations On Thr-308 And Ser-473 Leading To Its Activation And The Activated Form Translocates To The Nucleus
Colocalizes With Wdfy2 In Intracellular Vesicles
Molecular weight
55 kDa
Dilution range
WB 1:500-1:2000
ELISA 1:20000
Alternative names
Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody
Anti-Protein Kinase B antibody
Anti-Pkb antibody
Anti-Protein Kinase B Alpha antibody
Anti-Pkb Alpha antibody
Anti-Proto-Oncogene C-Akt antibody
Anti-Rac-Pk-Alpha antibody
Anti-AKT1 PKB RAC antibody
Protein name
Rac-Alpha Serine/Threonine-Protein Kinase
Protein Kinase B
Pkb
Protein Kinase B Alpha
Pkb Alpha
Proto-Oncogene C-Akt
Rac-Pk-Alpha
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 23.05.2024 

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