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Anti-AKT1 antibody (250-330)

Anti-AKT1 antibody (250-330)

Item no.	STJ91548-200
Manufacturer	St John's Laboratory
Amount	200 ug
Category	Oncology Neuroscience Aging & Neurological Disorders Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody, Anti-Protein Kinase B antibody, Anti-Pkb antibody, Anti-Protein Kinase B Alpha antibody, Anti-Pkb Alpha antibody, Anti-Proto-Oncogene C-Akt antibody, Anti-Rac-Pk-Alpha antibody, Anti-AKT1 PKB RAC antibody
Similar products	Anti-Rac-Alpha Serine/Threonine-Protein Kinase antibody Anti-Protein Kinase B antibody Anti-Pkb antibody Anti-Protein Kinase B Alpha antibody Anti-Pkb Alpha antibody Anti-Proto-Oncogene C-Akt antibody Anti-Rac-Pk-Alpha antibody
Available
Storage Conditions	Store at-20°C, and avoid repeat freeze-thaw cycles.
Molecular Weight	55 kDa
Description	Rabbit polyclonal to Akt1.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	250-330 aa
Tissue specificity	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
Cellular localization	Cytoplasm Nucleus Cell Membrane Nucleus After Activation By Integrin-Linked Protein Kinase 1 (Ilk1) Nuclear Translocation Is Enhanced By Interaction With Tcl1a Phosphorylation On Tyr-176 By Tnk2 Results In Its Localization To The Cell Membrane Where It Is Targeted For Further Phosphorylations On Thr-308 And Ser-473 Leading To Its Activation And The Activated Form Translocates To The Nucleus Colocalizes With Wdfy2 In Intracellular Vesicles
Clonality	Polyclonal
Protein name	Rac-Alpha Serine/Threonine-Protein Kinase Protein Kinase B Pkb Protein Kinase B Alpha Pkb Alpha Proto-Oncogene C-Akt Rac-Pk-Alpha
Gene symbol	AKT1
Dilution range	WB 1:500-1:2000 ELISA 1:20000
Note	For Research Use Only (RUO).
Immunogen Region	250-330 aa
Short Description	Rabbit polyclonal against Akt1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

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