Vergleich

Anti-MAP LC Beta antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB, IF, IHC-P
Menge 200ul
Host Rabbit
ArtNr STJ97398-200
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID
Q9GZQ8
Storage
Store at-20° C, and avoid repeat freeze-thaw cycles.
Description
MAP LC3 beta is a protein encoded by the MAP1LC3B gene which is approximately 14, 7 kDa. MAP LC3 beta is localised to the cytoplasm, cytoskeleton and autophagosome membrane. It is involved in pathways such as vesicle-mediated transport, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and the autophagy pathway. MAP LC3 beta is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and plays an important role in neurogenesis. MAP LC3 beta is expressed most abundantly in the heart, brain, skeletal muscle and testis and less expressed in liver. Mutations in the MAP1LC3B gene result in sporadic pheochromocytoma, lacrimal gland adenocarcinoma and spastic paraplegia STJ97398 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous MAP LC3 beta protein.
Gene ID
Gene symbol
Immunogen
Recombinant Protein
Short Description
Rabbit polyclonal against MAP LC beta
Tissue specificity
Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
Cellular localization
Cytoplasm
Cytoskeleton
Endomembrane System
Lipid-Anchor
Cytoplasmic Vesicle
Autophagosome Membrane
Autophagosome
Lc3-Ii Binds To The Autophagic Membranes
Localizes Also To Discrete Punctae Along The Ciliary Axoneme (By Similarity)
Dilution range
WB 1:1000-2000
IHC 1:200-500
IF 1:200
Alternative names
Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3b antibody
Anti-Autophagy-Related Protein Lc3 B antibody
Anti-Autophagy-Related Ubiquitin-Like Modifier Lc3 B antibody
Anti-Map1 Light Chain 3-Like Protein 2 antibody
Anti-Map1a/Map1b Light Chain 3 B antibody
Anti-Map1a/Map1b Lc3 B antibody
Anti-Microtubule-Associated Protein 1 Light Chain 3 Beta antibody
Anti-MAP1LC3B MAP1ALC3 antibody
Protein name
Microtubule-Associated Proteins 1a/1b Light Chain 3b
Autophagy-Related Protein Lc3 B
Autophagy-Related Ubiquitin-Like Modifier Lc3 B
Map1 Light Chain 3-Like Protein 2
Map1a/Map1b Light Chain 3 B
Map1a/Map1b Lc3 B
Microtubule-Associated Protein 1 Light Chain 3 Beta
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ul
Lieferbar: In stock
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Lieferung vsl. bis 06.06.2024 

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