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Anti-MAP1LC3B antibody

Anti-MAP1LC3B antibody

Item no.	STJ97398-200
Manufacturer	St John's Laboratory
Amount	200 ug
Category	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies Oligodendrocyte Markers Astroglia Markers
Type	Antibody Polyclonal
Applications	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3b antibody, Anti-Autophagy-Related Protein Lc3 B antibody, Anti-Autophagy-Related Ubiquitin-Like Modifier Lc3 B antibody, Anti-Map1 Light Chain 3-Like Protein 2 antibody, Anti-Map1a/Map1b Light Chain 3 B antibody, Anti-Map1a/Map1b Lc3 B antibody, Anti-Microtubule-Associated Protein 1 Light Chain 3 Beta antibody, Anti-MAP1LC3B MAP1ALC3 antibody
Similar products	Anti-Microtubule-Associated Proteins 1a/1b Light Chain 3b antibody Anti-Autophagy-Related Protein Lc3 B antibody Anti-Autophagy-Related Ubiquitin-Like Modifier Lc3 B antibody Anti-Map1 Light Chain 3-Like Protein 2 antibody Anti-Map1a/Map1b
Available
Short Description	Rabbit polyclonal against MAP LC beta
Description	MAP LC3 beta is a protein encoded by the MAP1LC3B gene which is approximately 14, 7 kDa. MAP LC3 beta is localised to the cytoplasm, cytoskeleton and autophagosome membrane. It is involved in pathways such as vesicle-mediated transport, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and the autophagy pathway. MAP LC3 beta is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and plays an important role in neurogenesis. MAP LC3 beta is expressed most abundantly in the heart, brain, skeletal muscle and testis and less expressed in liver. Mutations in the MAP1LC3B gene result in sporadic pheochromocytoma, lacrimal gland adenocarcinoma and spastic paraplegia STJ97398 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous MAP LC3 beta protein.
Formulation	PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide and 50% Glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	Recombinant Protein
Tissue specificity	Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.
Cellular localization	Cytoplasm Cytoskeleton Endomembrane System Lipid-Anchor Cytoplasmic Vesicle Autophagosome Membrane Autophagosome Lc3-Ii Binds To The Autophagic Membranes Localizes Also To Discrete Punctae Along The Ciliary Axoneme (By Similarity)
Clonality	Polyclonal
Protein name	Microtubule-Associated Proteins 1a/1b Light Chain 3b Autophagy-Related Protein Lc3 B Autophagy-Related Ubiquitin-Like Modifier Lc3 B Map1 Light Chain 3-Like Protein 2 Map1a/Map1b Light Chain 3 B Map1a/Map1b Lc3 B Microtubule-Associated Protein 1 Light Chain 3 Beta
Gene symbol	MAP1LC3B
Dilution range	WB 1:1000-2000 IHC 1:200-500 IF 1:200
Storage	Store at-20°C, and avoid repeat freeze-thaw cycles.
Note	For Research Use Only (RUO).

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

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