Anti-CACNA2D4 Antibody

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

CACNA2D4 antibody
Voltage-dependent calcium channel subunit alpha-2/delta-4 antibody
Voltage-gated calcium channel subunit alpha-2/delta-4 antibody
CACNA2D4 antibody

Unconjugated

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

CACNA2D4

IgG

For Research Use Only (RUO).

Store at -20C. Avoid freeze / thaw cycles.

Predominantly expressed in certain types of endocrine cells, Present in the Paneth cells of the small intestine, Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary, Present at low level in some brain regions such as the cerebellum (at protein level)