Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Isotype |
IgG |
Applications |
WB |
Amount |
50ul |
Host |
Rabbit |
Item no. |
STJ114175-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q7Z3S7 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 992-1115 of human CACNA2D4 (NP_758952. 4). |
Short Description |
Rabbit polyclonal against CACNA2D4 |
Tissue specificity |
Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level). |
Cellular localization |
MembraneSingle-Pass Type I Membrane Protein |
Molecular weight |
Calculated: 4kDa/109kDa/121kDa/123kDa/127kDa/129kDa. Observed: 128kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into-Voltage-Dependent Calcium Channel Subunit Alpha-2-4-Voltage-Dependent Calcium Channel Subunit Delta-4 antibodyAnti-CACNA2D4 antibody |
Protein name |
Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into-Voltage-Dependent Calcium Channel Subunit Alpha-2-4-Voltage-Dependent Calcium Channel Subunit Delta-4 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.