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Anti-SRPK1 antibody

Anti-SRPK1 antibody

Hersteller	St John's Laboratory
Kategorie	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Specific against	Human, Mouse
Isotype	IgG
Applikationen	WB, IF, IHC
Menge	100ul
Host	Rabbit
ArtNr	STJ114384-100
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q96SB4
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.
Gene ID	6732
Gene symbol	SRPK1
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 290-480 of human SRPK1 (NP_003128. 3).
Short Description	Rabbit polyclonal against SRPK1
Tissue specificity	Isoform 2 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 is only seen in the testis, at lower levels than isoform 2. Highly expressed in different erythroid and lymphoid cell lines, with isoform 2 being far more abundant than isoform 1.
Cellular localization	Isoform 2: Cytoplasm Nucleus Nucleus Matrix Microsome Shuttles Between The Nucleus And The Cytoplasm Inhibition Of The Hsp90 Atpase Activity Osmotic Stress And Interaction With Hhv-1 Icp27 Protein Can Induce Its Translocation To The Nucleus Kat5/Tip60 Inhibits Its Nuclear Translocation Isoform 1: Cytoplasm Mainly Localized In The Microsomal Fraction And The Cytoplasm And To A Lesser Extent In The Nuclear Matrix
Molecular weight	Calculated: 72kDa/74kDa/92kDa. Observed: 102kDa
Dilution range	WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
Alternative names	Anti-Srsf Protein Kinase 1 antibody Anti-Sfrs Protein Kinase 1 antibody Anti-Serine/Arginine-Rich Protein-Specific Kinase 1 antibody Anti-Sr-Protein-Specific Kinase 1 antibody Anti-SRPK1 antibody
Protein name	Srsf Protein Kinase 1 Sfrs Protein Kinase 1 Serine/Arginine-Rich Protein-Specific Kinase 1 Sr-Protein-Specific Kinase 1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	SRPK1_HUMAN

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Menge: 100ul

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