Vergleich

Anti-ACE2 antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Isotype IgG
Applikationen WB
Menge 100ul
Host Rabbit
ArtNr STJ114610-100
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification
Affinity purification
Uniprot ID
Q9BYF1
Storage
Store at-20° C and avoid freeze-thaw cycles.
Description
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ-and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Gene ID
Gene symbol
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 18-250 of human ACE2 (NP_068576. 1).
Short Description
Rabbit polyclonal against ACE2
Tissue specificity
Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells (at protein level). Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in the renal proximal tubule and the small intestine (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
Cellular localization
Processed Angiotensin-Converting Enzyme 2: Secreted
Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Detected In Both Cell Membrane And Cytoplasm In Neurons
Molecular weight
Calculated: 63kDa/92kDa. Observed: 110kDa
Dilution range
WB 1:500-1:2000
Alternative names
Anti-Angiotensin-Converting Enzyme 2 antibody
Anti-Ace-Related Carboxypeptidase antibody
Anti-Angiotensin-Converting Enzyme Homolog antibody
Anti-Aceh antibody
Anti-Metalloprotease Mprot15 Cleaved Into-Processed Angiotensin-Converting Enzyme 2 antibody
Anti-ACE2 UNQ868/PRO1885 antibody
Protein name
Angiotensin-Converting Enzyme 2
Ace-Related Carboxypeptidase
Angiotensin-Converting Enzyme Homolog
Aceh
Metalloprotease Mprot15 Cleaved Into-Processed Angiotensin-Converting Enzyme 2
Note
FOR RESEARCH USE ONLY (RUO).
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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Lieferung vsl. bis 23.05.2024 

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