Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Isotype |
IgG |
Applikationen |
WB |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
STJ114610-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9BYF1 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ-and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 18-250 of human ACE2 (NP_068576. 1). |
Short Description |
Rabbit polyclonal against ACE2 |
Tissue specificity |
Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells (at protein level). Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in the renal proximal tubule and the small intestine (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system. |
Cellular localization |
Processed Angiotensin-Converting Enzyme 2: SecretedCell MembraneSingle-Pass Type I Membrane ProteinCytoplasmDetected In Both Cell Membrane And Cytoplasm In Neurons |
Molecular weight |
Calculated: 63kDa/92kDa. Observed: 110kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Angiotensin-Converting Enzyme 2 antibodyAnti-Ace-Related Carboxypeptidase antibodyAnti-Angiotensin-Converting Enzyme Homolog antibodyAnti-Aceh antibodyAnti-Metalloprotease Mprot15 Cleaved Into-Processed Angiotensin-Converting Enzyme 2 antibodyAnti-ACE2 UNQ868/PRO1885 antibody |
Protein name |
Angiotensin-Converting Enzyme 2Ace-Related CarboxypeptidaseAngiotensin-Converting Enzyme HomologAcehMetalloprotease Mprot15 Cleaved Into-Processed Angiotensin-Converting Enzyme 2 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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