Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human, Mouse |
Isotype |
IgG |
Applikationen |
WB |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
STJ117646-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q9Y272 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168. 1). |
Short Description |
Rabbit polyclonal against RASD1 |
Tissue specificity |
Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues. |
Cellular localization |
Cell MembraneLipid-AnchorCytoplasmic SideCytoplasmPerinuclear RegionNucleus |
Molecular weight |
Calculated: 13kDa/31kDa. Observed: 31kDa |
Dilution range |
WB 1:200-1:2000 |
Alternative names |
Anti-Dexamethasone-Induced Ras-Related Protein 1 antibodyAnti-Activator Of G-Protein Signaling 1 antibodyAnti-RASD1 AGS1 DEXRAS1 antibody |
Protein name |
Dexamethasone-Induced Ras-Related Protein 1Activator Of G-Protein Signaling 1 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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