Anti-V-ATPase B1 antibody

Unconjugated

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Store at-20° C, and avoid repeat freeze-thaw cycles.

V-ATPase B1 is a protein encoded by the ATP6V1B1 gene which is approximately 56, 8 kDa. V-ATPase B1 is localised to the endomembrane system. It is involved in insulin receptor recycling, innate immune system, metabolism and mTOR signalling pathway. It mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis and synaptic vesicle proton gradient generation. V-ATPase B1 is expressed in the cochlea and endolymphatic sac. Mutations in the ATP6V1B1 gene may result in renal tubular acidosis with progressive nerve deafness. STJ96223 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of V-ATPase B1 protein.

ATP6V1B1

350-430 aa, C-terminal

Expressed in the cochlea and endolymphatic sac.

60 kDa

Anti-V-Type Proton Atpase Subunit B-Kidney Isoform antibody
Anti-V-Atpase Subunit B 1 antibody
Anti-Endomembrane Proton Pump 58 Kda Subunit antibody
Anti-Vacuolar Proton Pump Subunit B 1 antibody
Anti-ATP6V1B1 ATP6B1 VATB VPP3 antibody

FOR RESEARCH USE ONLY (RUO).