Anti-PRKAG3 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Human
Applikationen IF
Menge 50ul
Host Rabbit
ArtNr STJ116067-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Short Description
Rabbit polyclonal to PRKAG3
Alternative names
PRKAG3 antibody
5'-AMP-activated protein kinase subunit gamma-3 antibody
AMPK gamma3 antibody
AMPK subunit gamma-3 antibody
PRKAG3 antibody
AMPKG3 antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
IF 1:50 - 1:100
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
Recombinant protein of human PRKAG3
Iso type
IgG
Molecular weight
54.258 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Tissue specificity
Skeletal muscle, with weak expression in heart and pancreas
Uniprot id
Q9UGI9

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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