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Anti-PRKAG3 antibody

Anti-PRKAG3 antibody

Manufacturer	St John's Laboratory
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Hematology Lymphoma Cell Biology Obesity Cell Status Immunofluorescence Autophagy Primary Antibodies By Organ Pancreatic Cancer
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	IF
Amount	50ul
Host	Rabbit
Item no.	STJ116067-50
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q9UGI9
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Gene ID	53632
Gene symbol	PRKAG3
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PRKAG3 (NP_059127. 2).
Short Description	Rabbit polyclonal against PRKAG3
Tissue specificity	Skeletal muscle, with weak expression in heart and pancreas.
Molecular weight	Calculated: 51kDa/54kDa. Observed:
Dilution range	IF 1:50-1:100
Alternative names	Anti-5'-Amp-Activated Protein Kinase Subunit Gamma-3 antibody Anti-Ampk Gamma3 antibody Anti-Ampk Subunit Gamma-3 antibody Anti-PRKAG3 AMPKG3 antibody
Protein name	5'-Amp-Activated Protein Kinase Subunit Gamma-3 Ampk Gamma3 Ampk Subunit Gamma-3
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	AAKG3_HUMAN

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 5/23/2024