Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applikationen |
WB |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
STJ116732-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q8NFG4 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human FLCN (NP_653207. 1). |
Short Description |
Rabbit polyclonal against FLCN |
Tissue specificity |
Expressed in most tissues tested, including skin, lung, kidney, heart, testis and stomach. |
Cellular localization |
Lysosome MembraneCytoplasmCytosolCell ProjectionCiliumCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleNucleusLocalizes To Lysosome Membrane In Amino Acid-Depleted Conditions And Relocalizes To The Cytosol Upon RefeedingColocalizes With Fnip1 And Fnip2 In The CytoplasmAlso Localizes To Motile And Non-Motile CiliaCentrosomes And The Mitotic Spindle |
Molecular weight |
Calculated: 20kDa/37kDa/64kDa. Observed: 75kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Folliculin antibodyAnti-Bhd Skin Lesion Fibrofolliculoma Protein antibodyAnti-Birt-Hogg-Dube Syndrome Protein antibodyAnti-FLCN BHD antibody |
Protein name |
FolliculinBhd Skin Lesion Fibrofolliculoma ProteinBirt-Hogg-Dube Syndrome Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
|
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