Manufacturer |
St John's Laboratory
|
Category |
|
Type |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applications |
WB |
Amount |
50ul |
Host |
Rabbit |
Item no. |
STJ116732-50 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification |
Affinity purification |
Uniprot ID |
Q8NFG4 |
Storage |
Store at-20° C and avoid freeze-thaw cycles. |
Description |
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human FLCN (NP_653207. 1). |
Short Description |
Rabbit polyclonal against FLCN |
Tissue specificity |
Expressed in most tissues tested, including skin, lung, kidney, heart, testis and stomach. |
Cellular localization |
Lysosome MembraneCytoplasmCytosolCell ProjectionCiliumCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleNucleusLocalizes To Lysosome Membrane In Amino Acid-Depleted Conditions And Relocalizes To The Cytosol Upon RefeedingColocalizes With Fnip1 And Fnip2 In The CytoplasmAlso Localizes To Motile And Non-Motile CiliaCentrosomes And The Mitotic Spindle |
Molecular weight |
Calculated: 20kDa/37kDa/64kDa. Observed: 75kDa |
Dilution range |
WB 1:500-1:2000 |
Alternative names |
Anti-Folliculin antibodyAnti-Bhd Skin Lesion Fibrofolliculoma Protein antibodyAnti-Birt-Hogg-Dube Syndrome Protein antibodyAnti-FLCN BHD antibody |
Protein name |
FolliculinBhd Skin Lesion Fibrofolliculoma ProteinBirt-Hogg-Dube Syndrome Protein |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.