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Anti-WASF1 antibody

Anti-WASF1 antibody

Hersteller	St John's Laboratory
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Western Blot Primary Antibodies By Organ Breast Cancer
Typ	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applikationen	WB
Menge	100ul
Host	Rabbit
ArtNr	STJ116831-100
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Clonality	Polyclonal
Conjugation	Unconjugated
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification	Affinity purification
Uniprot ID	Q92558
Storage	Store at-20° C and avoid freeze-thaw cycles.
Description	The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID	8936
Gene symbol	WASF1
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107. 1).
Short Description	Rabbit polyclonal against WASF1
Tissue specificity	Highly expressed in brain. Lowly expressed in testis, ovary, colon, kidney, pancreas, thymus, small intestine and peripheral blood.
Cellular localization	Cytoplasm Cytoskeleton Cell Junction Synapse Focal Adhesion Dot-Like Pattern In The Cytoplasm Concentrated In Rac-Regulated Membrane-Ruffling Areas Partial Translocation To Focal Adhesion Sites Might Be Mediated By Interaction With Sorbs2 In Neurons Colocalizes With Activated Ntrk2 After Bdnf Addition In Endocytic Sites Through The Association With Tmem108
Molecular weight	Calculated: 61kDa. Observed: 62kDa
Dilution range	WB 1:500-1:2000
Alternative names	Anti-Wiskott-Aldrich Syndrome Protein Family Member 1 antibody Anti-Wasp Family Protein Member 1 antibody Anti-Protein Wave-1 antibody Anti-Verprolin Homology Domain-Containing Protein 1 antibody Anti-WASF1 KIAA0269 SCAR1 WAVE1 antibody
Protein name	Wiskott-Aldrich Syndrome Protein Family Member 1 Wasp Family Protein Member 1 Protein Wave-1 Verprolin Homology Domain-Containing Protein 1
Note	FOR RESEARCH USE ONLY (RUO).
Swiss port key	WASF1_HUMAN

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