Vergleich

Anti-ABCG2 antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Applikationen WB, IF, ELISA, IHC-P
Menge 100ul
Host Rabbit
ArtNr STJ97253-100
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Conjugation
Unconjugated
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Uniprot ID
Q9UNQ0
Storage
Store at-20° C, and avoid repeat freeze-thaw cycles.
Concentration
1 mg/ml
Description
ABCG2 is a protein encoded by the ABCG2 gene which is approximately 72, 3 kDa. ABCG2 is localised to the cell membrane and mitochondrion membrane. It is involved in the Gefitinib pathway, Irinotecan pathway, and pyrimidine metabolism. It is a high-capacity urate exporter functioning in both renal and extrarenal urate excretion. It plays a role in porphyrin homeostasis as it is able to mediate the export of protoporhyrin IX both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. ABCG2 is highly expressed in the placenta. Mutations in the ABCG2 gene may result in erythroplakia and hyperuricemia. STJ97253 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ABCG2 protein.
Gene ID
Gene symbol
Immunogen
Synthesized peptide derived from human ABCG2.
Immunogen region
461-510 aa, Internal
Short Description
Rabbit polyclonal against ABCG2
Tissue specificity
Highly expressed in placenta. Low expression in small intestine, liver and colon. Expressed in brain (at protein level).
Cellular localization
Cell Membrane
Multi-Pass Membrane Protein
Apical Cell Membrane
Mitochondrion Membrane
Enriched In Membrane Lipid Rafts
Dilution range
IF 1:50-200
WB 1:500-1:2000
IHC-p 1:100-1:300
ELISA 1:10000
Alternative names
Anti-Broad Substrate Specificity Atp-Binding Cassette Transporter Abcg2 antibody
Anti-Atp-Binding Cassette Sub-Family G Member 2 antibody
Anti-Breast Cancer Resistance Protein antibody
Anti-Cdw338 antibody
Anti-Mitoxantrone Resistance-Associated Protein antibody
Anti-Placenta-Specific Atp-Binding Cassette Transporter antibody
Anti-Urate Exporter antibody
Anti-Cd Antigen Cd338 antibody
Anti-ABCG2 ABCP BCRP BCRP1 MXR antibody
Protein name
Broad Substrate Specificity Atp-Binding Cassette Transporter Abcg2
Atp-Binding Cassette Sub-Family G Member 2
Breast Cancer Resistance Protein
Cdw338
Mitoxantrone Resistance-Associated Protein
Placenta-Specific Atp-Binding Cassette Transporter
Urate Exporter
Cd Antigen Cd338
Note
FOR RESEARCH USE ONLY (RUO).
Swiss port key

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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Lieferung vsl. bis 25.04.2024 

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