Hersteller |
St John's Laboratory
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Applikationen |
WB, IF, ELISA, IHC-P |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
STJ97253-100 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Conjugation |
Unconjugated |
Formulation |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Uniprot ID |
Q9UNQ0 |
Storage |
Store at-20° C, and avoid repeat freeze-thaw cycles. |
Concentration |
1 mg/ml |
Description |
ABCG2 is a protein encoded by the ABCG2 gene which is approximately 72, 3 kDa. ABCG2 is localised to the cell membrane and mitochondrion membrane. It is involved in the Gefitinib pathway, Irinotecan pathway, and pyrimidine metabolism. It is a high-capacity urate exporter functioning in both renal and extrarenal urate excretion. It plays a role in porphyrin homeostasis as it is able to mediate the export of protoporhyrin IX both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. ABCG2 is highly expressed in the placenta. Mutations in the ABCG2 gene may result in erythroplakia and hyperuricemia. STJ97253 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ABCG2 protein. |
Gene ID |
|
Gene symbol |
|
Immunogen |
Synthesized peptide derived from human ABCG2. |
Immunogen region |
461-510 aa, Internal |
Short Description |
Rabbit polyclonal against ABCG2 |
Tissue specificity |
Highly expressed in placenta. Low expression in small intestine, liver and colon. Expressed in brain (at protein level). |
Cellular localization |
Cell MembraneMulti-Pass Membrane ProteinApical Cell MembraneMitochondrion MembraneEnriched In Membrane Lipid Rafts |
Dilution range |
IF 1:50-200WB 1:500-1:2000IHC-p 1:100-1:300ELISA 1:10000 |
Alternative names |
Anti-Broad Substrate Specificity Atp-Binding Cassette Transporter Abcg2 antibodyAnti-Atp-Binding Cassette Sub-Family G Member 2 antibodyAnti-Breast Cancer Resistance Protein antibodyAnti-Cdw338 antibodyAnti-Mitoxantrone Resistance-Associated Protein antibodyAnti-Placenta-Specific Atp-Binding Cassette Transporter antibodyAnti-Urate Exporter antibodyAnti-Cd Antigen Cd338 antibodyAnti-ABCG2 ABCP BCRP BCRP1 MXR antibody |
Protein name |
Broad Substrate Specificity Atp-Binding Cassette Transporter Abcg2Atp-Binding Cassette Sub-Family G Member 2Breast Cancer Resistance ProteinCdw338Mitoxantrone Resistance-Associated ProteinPlacenta-Specific Atp-Binding Cassette TransporterUrate ExporterCd Antigen Cd338 |
Note |
FOR RESEARCH USE ONLY (RUO). |
Swiss port key |
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