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Anti-SMAD7 Antibody

Anti-SMAD7 Antibody

Hersteller	St John's Laboratory
Kategorie	Antibody
Typ	Antibody
Specific against	Mouse, Rat
Applikationen	WB
Menge	50ul
Host	Rabbit
ArtNr	STJ114223-50
eClass 6.1	32160702
eClass 9.0	32160702
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Description	The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Short Description	Rabbit polyclonal to SMAD7
Alternative names	SMAD7 antibody Mothers against decapentaplegic homolog 7 antibody MAD homolog 7 antibody Mothers against DPP homolog 7 antibody Mothers against decapentaplegic homolog 8 antibody MAD homolog 8 antibody Mothers against DPP homolog 8 antibody SMAD family member 7 antibody SMAD 7 antibody Smad7 antibody hSMAD7 antibody SMAD7 antibody MADH7 antibody MADH8 antibody
Clonality	Polyclonal
Conjugation	Unconjugated
Dilution range	WB 1:500 - 1:2000
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id	4092
Gene symbol	SMAD7
Immunogen	A synthetic peptide of human SMAD7
Iso type	IgG
Molecular weight	46.426 kDa
Note	For Research Use Only (RUO).
Purification	Affinity purification
Storage instruction	Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key	O15105
Tissue specificity	Ubiquitous with higher expression in the lung and vascular endothelium
Uniprot id	O15105

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STJ114223-50-datasheet.pdf

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Menge: 50ul

Listenpreis: 235,71 €

Preis: 235,71 €

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