Antibodies

Anti-SMAD7 Antibody

Hersteller St John's Laboratory
Kategorie
Typ Antibody
Specific against Mouse, Rat
Applikationen WB
Menge 50ul
Host Rabbit
ArtNr STJ114223-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Description
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
Short Description
Rabbit polyclonal to SMAD7
Alternative names
SMAD7 antibody
Mothers against decapentaplegic homolog 7 antibody
MAD homolog 7 antibody
Mothers against DPP homolog 7 antibody
Mothers against decapentaplegic homolog 8 antibody
MAD homolog 8 antibody
Mothers against DPP homolog 8 antibody
SMAD family member 7 antibody
SMAD 7 antibody
Smad7 antibody
hSMAD7 antibody
SMAD7 antibody
MADH7 antibody
MADH8 antibody
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution range
WB 1:500 - 1:2000
Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene id
Gene symbol
Immunogen
A synthetic peptide of human SMAD7
Iso type
IgG
Molecular weight
46.426 kDa
Note
For Research Use Only (RUO).
Purification
Affinity purification
Storage instruction
Store at -20C. Avoid freeze / thaw cycles.
Swiss prot key
Tissue specificity
Ubiquitous with higher expression in the lung and vascular endothelium
Uniprot id
O15105

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Menge: 50ul
Lieferbar: In stock
Listenpreis: 235,71 €
Preis: 235,71 €
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