Auraptene

ArtNr	TMO-T4115-20mg
Hersteller	TargetMol
CAS-Nr.	495-02-3
Menge	20 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 20 mg 25 mg 500 mg 50 mg 5 mg
Kategorie	Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Reagents & Chemicals Molecules
Typ	Molecules
Specific against	other
Citations	1.Murakami, A.,Nakamura, Y.,Tanaka, T., et al. Suppression by citrus auraptene of phorbol ester- and endotoxin-induced inflammatory responses: Role of attenuation of leukocyte activation. Carcinogenesis 21(10), 1843-1850 (2000).
Smiles	CC(C)=CCCC(C)=CCOc1ccc2ccc(=O)oc2c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	7-geranyloxycoumarin
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Targets	BACE\|\|\|MMP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	298.38
Description	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.
Pathways	Neuroscience\|\|\|Proteases/Proteasome
Bioactivity	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis.1 When examined for its potential use in Alzheimerâ€™s disease treatment, auraptene was shown to inhibit beta-secretase (BACE1) activity with an IC50 value of 345.1 uM.
Receptor	BACE1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

TMO-T4115-20mg-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 20 mg

lieferbar

Technische Frage stellen