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Cynomolgus Thrombopoietin R / TPO R Protein, His Tag (MALS & SPR verified)

Cynomolgus Thrombopoietin R / TPO R Protein, His Tag (MALS & SPR verified)

ArtNr	THR-C52H3-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Format	Solid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	90%
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	54.3 kDa
Description	Cynomolgus Thrombopoietin R Protein, His Tag (THR-C52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Thr 489 (Accession # A0A2K5UGC7).
Background	Thrombopoietin R, also known as TPO-R, is expressed predominantly on the surface of MKs, platelets, hemangioblasts, and hematopoietic stem cells (HSCs). Binding of TPO to the megakaryocyte TPO-R leads to different effects: prevention of megakaryocyte apoptosis; increased megakaryocyte number, size, and ploidy; increasing rate of megakaryocyte maturation; and internalization of the TPO/TPO-R complex. Thrombopoietin R involved in multiple signal transduction pathways, such as JAK, STAT, and MAP kinase.
Molecule	Thrombopoietin R
Exp Region	Gln 22 - Thr 489
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 54.3 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

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Menge: 100 ug

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Lieferung vsl. bis 19.06.2025

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