Cyclin Dependent Kinase 2-associated Protein 1 (CDK2 Associated Protein 1, CDK2-associated Protein 1, CDK2AP1, Deleted in Oral Cancer 1, DOC 1, DOC1, DOC-1, DOC 1-related Protein, DOC 1R, DOC1R, DOC-1R, Putative Oral Can

Antibodies / Antibodies-Protein Kinases

-20°C

Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

Partial recombinant sequence from Cyclin Dependent Kinase 2-associated Protein 1.

The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes

Applications:
Suitable for use in Western Blot, Dot Blot and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Immunocytochemistry: 2-100ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.