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Hemagglutinin-Esterase, Recombinant, Bovine Coronavirus, aa19-424, His-Tag (HE)

ArtNr USB-370571
Hersteller United States Biological
Menge 20 ug
Quantity options 20 ug 100 ug
Kategorie
Typ Enzymes
Format Liquid
Specific against other
Purity ≥90% (SDS-PAGE)
ECLASS 10.1 32160410
ECLASS 11.0 32160410
UNSPSC 12352204
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Molecular Biology / MB-Infectious Disease
Shipping Temperature
Blue Ice
Storage Conditions
-20°C
Molecular Weight
47, 7
Grade
Purified
Form
Supplied as a liquid in Tris, 50% glycerol.
EU Commodity Code
30021019
Description
Structural protein that makes short spikes at the surface of the virus. Contains receptor binding and receptor-destroying activities. Mediates de-O-acetylation of N-acetyl-9-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells. This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell. May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one. Seems to be a 'luxury' protein that is not absolutely necessary for virus infection in culture. However, its presence in the virus may alter its pathogenicity. May become a target for both the humoral and the cellular branches of the immune system.

Source:
Recombinant protein corresponding to aa19-424 from bovine Coronavirus HE, fused to His-Tag at N-terminal, expressed in yeast.

Molecular Weight:
~47.7kD

AA Sequence:
FDNPPTNVVSHLNGDWFLFGDSRSDCNHVVNTNPRNYSYMDLNPALCDSGKISSKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCTTSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYSYGRCPTAADINTPDVPICVYDPLPLILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shelf Life
6 months

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
lieferbar

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