1-Methylpsilocin

Blue Ice

218, 29

Supplied as a brown solid.

Potent and selective 5-HT2C agonist (IC50 values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (Ki = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.

Synonyms:
3-[2-(Dimethylamino)ethyl]-1-methylindol-4-ol

CAS Number:
1465-16-3

Molecular Weight:
218.29

Molecular Formula:
C13H18N2O

Solubility:
DMSO to 100mM, ethanol to 10mM

Method for Determining Identity:
Proton NMR and Mass Spectrometric analysis

Melting Point:
125-127°C

Appearance:
Supplied as a brown solid.

Purity:
≥99% (HPLC)

Storage and Stability:
Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.