Endoglin / CD105 (ENG) Antibody (PerCP)

Aliquot and store in the dark at 2C to 8C. Avoid exposure to light.

Reacts with a homodimeric integral membrane protein comprised of 95Kd subunits (CD105). CD105 is a component of the TGF-B receptor system and can bind TGF-B1 and TGF-B3 with high affinity but does not bind TGF-B2. CD105 is expressed by vascular endothelial cells and syncytiotrophoblasts of placenta, Pre-B cells in fetal marrow, erythroid precursors in fetal and adult bone marrow and is weakly expressed by stromal fibroblasts. U937 cells and monocytes and tissue macrophages also expresses CD105. Expression of CD105 is increased on activated endothelium in tissues undergoing angiogenesis, such as in tumours, or in cases of wound healing or dermal inflammation.

The reagent is provided in aqueous buffered solution containing protein stabilizer, and <=0.09% sodium Azide

This product is for research use only.

EGLN_HUMAN

131195