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T-Cell-Specific Surface Glycoprotein CD28 (CD28) Antibody (FITC) Europäischer Partner

ArtNr abx200212
Hersteller Abbexa
Menge 100 tests
Kategorie
Typ Antibody Primary
Applikationen FC
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host Mouse
Isotype IgG1
Konjugat/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Conjugate / Tag
FITC
Storage Conditions
Aliquot and store in the dark at 2C to 8C. Avoid exposure to light.
Molecular Weight
44 kDa
Description
The CD28.2 monoclonal antibody specifically binds to CD28, a 44 kDa homodimeric transmembrane glycoprotein present on most mature T cells, thymocytes and plasma cells. CD28 is a costimulatory receptor that binds CD80 and CD86 as ligands and plays a very important role in T cell-B cell interactions. It has been suggested that CD28 initiates and regulates a separate and distinct signal transduction pathway from those stimulated by the TCR complex. Additionally, it has been reported that CD28 antibody clones vary in their ability to stimulate T cells to produce IL-2 and increase intracellular Ca2+ concentration. This finding suggests the existence of functionally distinct subregions on the CD28 molecule. CD28.2 has been demonstrated to bind to the same molecule as clone L293, another CD28 mAb, and has been reported to induce Ca2+ influx in Jurkat T cells.
Dry Ice
No
Buffer
The reagent is provided in aqueous buffered solution containing protein stabilizer, and <=0.09% sodium Azide
Note
This product is for research use only.
Purification
Affinity Chromatography
Antigen
T-Cell-Specific Surface Glycoprotein CD28 (CD28)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 tests
Lieferbar: In stock
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