KCNIP3 Rabbit pAb

Polyclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KCNIP3 (NP_038462.1).

29kDa

Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Neuroscience, Calcium Signaling, Cardiovascular, Blood.

30818

KCNIP3