Recombinant Mouse IL-4 Protein

< 0.1 EU/μg of the protein by LAL method.

ice pack

14.15 kDa

Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It enhances both secretion and cell surface expression of IgE and IgG1. Interleukin-4 / IL4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Interleukin-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype.

C-His

B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, Il-4, IGG1 induction factor, Lymphocyte stimulatory factor 1

1. Measured in a cell proliferation assay using MC/9 2 mouse mast cells. The ED₅₀ for this effect is 2. 8-11. 3 pg/mL, corresponding to a specific activity of 8. 85×10⁷~3. 57×10⁸ units/mg.|2. Measured in a cell proliferation assay using HT-2 mouse T cells. The ED₅₀ for this effect is 0. 21-0. 85 ng/mL, corresponding to a specific activity of 1. 18×10⁶~4. 76×10⁶ units/mg.

14.15 kDa