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Anti-Annexin A5 (ANXA5)

ArtNr ARP-20-2500
Hersteller American Research Products
Menge 50 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC, ICC, ELISA
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ANXV, ANX5, ANX-V, ENX2, PP4, ANX-A5, Annexin V
Lieferbar
Description
  • Annexin A5 (or annexin V) is a cellular protein in the annexin group. The function of the protein is unknown, however annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. These properties have been found by in vitro experiments. Antibodies directed against annexin A5 are the cause of a syndrome called the antiphospholipid syndrome.
  • Annexin A5 is used as a probe in the annexin A5 affinity assay to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis as well as other forms of cell death. Platelets also expose phosphatidylserine on their surface when activated, which serves as binding site for various coagulation factors.
Form
Liquid
Working Dilution
Western blotting: 1:100-400, Immunocytochemistry in formalin fixed cells: 1:100-500, Immunohistochemistry in formalin fixed frozen section: 1:100-500, Immunohistochemistry in paraffin section: 1:50-417
Storage
2-8C for immediate use, or at -20C (aliquot)
Synonyms
ANXV, ANX5, ANX-V, ENX2, PP4, ANX-A5, Annexin V
Concentration
0.2mg/ml
Antigen Recognized in Species
Rat
Purification
Affinity chromatography

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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