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Activin A (E.coli-derived), Human/Mouse/Rat, Recombinant

Activin A (E.coli-derived), Human/Mouse/Rat, Recombinant

ArtNr	ARP-28-10052E-1
Hersteller	American Research Products
Menge	1 mg
Quantity options	1 mg 10 ug 2 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Purity	0,97
Sequence	GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Description	Activin A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, follistatin. Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues.
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Purity	0, 97
Source	E. Coli
Interest Fields	Angiogenesis/Cardiovascular, Apoptosis, Cancer, Neurobiology, Stem Cells &, Differentiation, TGF- beta Superfamily
Amino Acid Sequence	GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
Endotoxin Level	Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug).
Biological Activity	The ED 50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is a‰¤ 2.0 ng/ml, corresponding to a specific activity of a‰¥ 5 x 10^5 units/mg.
Protein Content	Verified by UV Spectroscopy and/or SDS-PAGE gel.
Authenticity	Verified by N-terminal and Mass Spectrometry analyses (when applicable).

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Menge: 1 mg

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