Comparison

Activin A (E.coli-derived), Human/Mouse/Rat, Recombinant

Item no. ARP-28-10052E-1
Manufacturer American Research Products
Amount 1 mg
Quantity options 1 mg 10 ug 2 ug
Category
Type Proteins Recombinant
Specific against other
Purity 0,97
Sequence GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Description
Activin A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, follistatin. Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two betaA chains, each containing 116 amino acid residues.
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Purity
0, 97
Source
E. Coli
Interest Fields
Angiogenesis/Cardiovascular, Apoptosis, Cancer, Neurobiology, Stem Cells &, Differentiation, TGF- beta Superfamily
Amino Acid Sequence
GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS
Endotoxin Level
Endotoxin level is <, 0.1 ng/ug of protein (<, 1EU/ug).
Biological Activity
The ED 50 as determined by its ability to inhibit the proliferation of murine MPC-11 cells is a‰¤ 2.0 ng/ml, corresponding to a specific activity of a‰¥ 5 x 10^5 units/mg.
Protein Content
Verified by UV Spectroscopy and/or SDS-PAGE gel.
Authenticity
Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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