Mouse Monoclonal Antibody to HSP70

Mouse IgG1

MW: 70kDa
Enterez GeneID: 3308
General Information: This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.
Immunogen: Purified recombinant fragment of human HSP70 expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Ascitic fluid containing 0.03% sodium azide. ;
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: 1 to 200 - 1 to 1000; ICC: 1 to 200 - 1 to 1000
References: 1. J Invest Dermatol. 1992 Dec; 99(6):734-42. ; 2. Nature. 1997 Aug 7; 388(6642):548-54. ; 3. Exp Neurol. 2002 Nov; 178(1):104-11. ; 4. Science. 2004 May 7; 304(5672):870-5.