Mouse Monoclonal Antibody to RAD18

Mouse IgG1

MW: 56.2kDa
Enterez GeneID: 56852
General Information: The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.;
Immunogen: Purified recombinant fragment of human RAD18 (AA: 332-430) expressed in E. Coli.
Size and Concentration: 100ug/1mg/ml
Supplied As: Lyophilized Powder from 100ul of Purified antibody in PBS with 0.05% sodium azide
Reconstitution and Storage: Reconstituted with 100ul sterile DI H2O, at stored at 4C or -20C for short or long term storage.
Applications: ELISA: 1 to 10000; WB: 1 to 500 - 1 to 2000; IHC: ; ICC: ; FCM: 1 to 200 - 1 to 400
References: 1.Mol Cancer. 2014 Jun 3; 13:137. ; 2.J Hematol Oncol. 2014 Mar 30; 7:28. ;