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Anti-Kir6.1 Potassium Channel Antibody

ArtNr 75-394
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ICC
Clon N366/60
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ATP-sensitive inward rectifier potassium channel 8 (Inward rectifier K(+) channel Kir6.1) (Potassium channel, inwardly rectifying subfamily J member 8) (uKATP-1)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Kir6.1 potassium channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
45 kDa
Manufacturer - Research Area
Ion Channels and Modulators, K+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 306-424 (cytoplasmic C-terminus) of rat Kir6.1 (accession number Q63664) produced recombinantly in E. Coli
Immunogen Species
Rat
Description
Our Anti-Kir6.1 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N366/60. It detects mouse and rat Kir6.1 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description
ATP-sensitive inward rectifier potassium channel 8 or Kir6.1 is encoded by the gene Kcnj8. Kir6.1 is an integral membrane protein which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. In this manner, Kir6.1 plays a role in modifying Ca2+ release from intracellular stores. Kir6.1 is expressed in many tissues including in pancreatic islets, brain, skeletal muscle and heart and found distributed in mitochondria and endoplasmic reticulum. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS) and Cantu Syndrome.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with Kir6.2
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application
WB Brain
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Kir6.1 potassium channel mouse monoclonal primary antibody from hybridoma clone N366/60. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 11.09.2025 

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