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Anti-Kv1.1 K+ Channel Antibody

Anti-Kv1.1 K+ Channel Antibody

ArtNr	75-007
Hersteller	Antibodies Incorporated
Menge	100 uL
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunoprecipitation Primary Antibodies Immunoblot
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Clon	K20/78
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)
Versandbedingung	Gekühlt
Lieferbar
Specificity	Finch, Human, Mouse, Rabbit, and Rat
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Kv1.1 K+ channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	85 kDa (major: mature glycosylation), 65 kDa (minor: immature glycosylation)
Manufacturer - Research Area	Ion Channels and Modulators, K+ Channels
Expiration	24 months from date of receipt
Immunogen	Synthetic peptide amino acids 458-476 (cytoplasmic C-terminus) of rat Kv1.1 (EEDMNNSIAHYRQANIRTG; accession number P10499)
Immunogen Species	Rat
Target Description	Potassium Channel Kv1.1 or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Manufacturer - Format	Liquid
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Dilution Range: WB	1:500
Dilution Range: IHC	1:250
Dilution Range: ICC	1:500
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Kv1.1 K+ channel mouse monoclonal primary antibody from hybridoma clone K20/78. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 12.06.2025

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