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Anti-Ankyrin-G (Staining) Antibody

ArtNr 75-146-020
Hersteller Antibodies Incorporated
Menge 20 uL
Quantity options 100 uL 20 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IP, IHC, ICC
Clon N106/36
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Hamster, Cat (Feline, Felis catus), Primate
Host Mouse
Isotype IgG2a
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ankyrin-3 (ANK-3) (Ankyrin-G)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Ankyrin-G (Staining)
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
<200 kDa
Manufacturer - Research Area
Cell Markers, Neuronal Markers, Axonal Markers, Scaffold Proteins
Expiration
24 months from date of receipt
Immunogen
Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Our Anti-Ankyrin-G (Staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N106/36. It detects feline, hamster, human, mouse, non-human primate, and rat Ankyrin-G (Staining), and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Target Description
Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with Ankyrin-B
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.73
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
Quality Control: Application
IHC
Dilution Range: WB
1:1000
Dilution Range: IHC
1:500
Dilution Range: ICC
1:500
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Ankyrin-G (Staining) mouse monoclonal primary antibody from hybridoma clone N106/36. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 uL
Lieferbar: In stock
lieferbar

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