Alpk1 Rabbit mAb

Monoclonal Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

α- Protein Kinase 1, also known as α- ALPK1 is associated with chronic kidney disease (CKD), myocardial infarction, gout and type 2 diabetes. According to reports, ALPK1 mutations can lead to serious deficits in motor coordination in mice. ALPK1 can enhance the expression of pro-inflammatory cytokines, including IL-1, in cultured human THP1 and human embryonic kidney 293 (HEK293) cells (PMID: 31557402, PMID: 26275947) β, IL-8 and TGF- β 1. The ALPK1 short subtype (108 kDa) is highly expressed in the brain, spinal cord, heart, lungs, spleen, thymus, small intestine, skin, and testes, while detecting skeletal muscle and kidney. ALPK1 isoform (130 kDa) appears in the heart, lungs, thymus, and skin

WB, 1:2000 - 1:9000|IHC-P, 1:50 - 1:200

Signal transduction protein transport vesicle transport regulation