Anti-Orai1 Antibody

ArtNr	ABC-ABO11166
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ORAI1, CRACM1, TMEM142A, Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A
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Primary Accession	Q96D31
Application	WB
Clonality	Polyclonal
Gene ID	84876
Reactivity	H, M, Rat
Legend image 1	Anti- Orai1 antibody, ABO11166, Western blottingAll lanes: Anti Orai1 (ABO11166) at 0.5ug/mlWB: SKOV Whole Cell Lysate at 40ugPredicted bind size: 33KDObserved bind size: 50KD
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Calculated MW	32668
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Calcium release-activated calcium channel protein 1(ORAI1) detection. Tested with WB in Human; Mouse; Rat.
Protein Function	Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. .
Subcellular Localization	Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome . Isoform beta is more mobile in the plasma membrane. Colocalizes with UBQLN1 in the autophagosome. .
Protein Name	Calcium release-activated calcium channel protein 1
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human Orai1(278-301aa EFARLQDQLDHRGDHPLTPGSHYA), different from the related rat and mouse sequences by two amino acids.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the Orai family.

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ABC-ABO11166-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 02.10.2025

Express-Lieferung: 22 Tage sparen

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